Product information

Mirena® (Levonorgestrel)

Title

Mirena®: benefits beyond contraception for up to 8 years*1

Mirena® benefits

Long-term efficacy with
a more favorable bleeding
profile than the Copper IUD2,3

Mirena® is now approved
for 8 years of contraceptive use.*1,2

More information

IUD – intrauterine device

Title

Mirena® now provides the peace of mind of continuous contraceptive protection for up to 8 years1

 

Mirena® provides long-lasting protection from an unintended pregnancy1

 

Mirena® contraceptive efficacy

More than
99%
contraceptive efficacy
after 5 years and
up to 8 years*1

0.7
Cumulative failure
rate at Years 1–5*1

0.68
Cumulative failure
rate at Years 6–8†2

More information

Mirena®: protect your patients with effective, long-lasting contraception1

IUD – intrauterine device

Title

The favorable benefit/risk profile of Mirena® has now been demonstrated through 8 years of use1,2

 

The safety profile of Mirena® at:

 

Contraceptive duration of use

8 years
of use

is comparable
to the safety
profile at

5 years
of use1,2

Reassure your patients with a favorable benefit/risk profile over the long term1, 2

Title

With Mirena®, she can enjoy benefits beyond contraception with a reduction in menstrual bleeding.1,2

 

Discontinuation rates for both devices vary, but discontinuation due to bleeding tends to be lower with the LNG-IUS than with the Copper IUD1,3

 

Mirena bleeding benefit

~40% of Copper IUD
users experience heavy
or prolonged bleeding1

~90% of women who use
LNG-IUS like Mirena® report
a reduction in bleeding
at 1 year1

Please note, these figures are drawn from separate
studies and so are not directly comparable.

Amenorrhea in women using Mirena®

Offer your patient Mirena® so she can experience fewer bleeding days than with a Copper IUD4

Title

Give her the confidence to focus on her family or career without the fear of an unintended pregnancy1,2

 

Confidence without fear of an unintended pregnancy

It is important to remember
that perimenopausal symptoms
do not signal an end to fertility.

More information

For women over 40 years of age, reliable protection and convenience are of paramount importance when choosing contraception*

Title

Mirena®: satisfaction that comes from extended contraceptive confidence1

 

Patient satisfaction

Mirena® delivers high
rates of satisfaction:

98.7%
of women who used
Mirena® for
8 years*†1

More information

Offer her satisfaction and peace of mind with her contraceptive choice1

  • Jensen JT et al. Am J Obstet Gynecol 2022;227(6):873.e1–873.e12. Return to content
Title

Continuation rates, like satisfaction rates, were highest with the LNG-IUS1

 

Continuation at 12 months1

 

Patient satisfaction

LNG-IUS

Copper IUD

Implant

Depot medroxyprogesterone acetate

Oral contraceptives

Patch

Ring

88%

84%

83%

57%

55%

49%

54%

Mirena®: long-lasting pregnancy protection with a favorable bleeding profile2,3

IUD – intrauterine device; LNG-IUS – levonorgestrel-releasing intrauterine system

Please click here to see the essential information for Mirena®

 

Title

Mirena®: Frequently asked questions

Below you will find answers to some commonly asked questions about the use of Mirena® for the treatment of heavy menstrual bleeding. These will support you when assessing appropriate treatment options for women in your clinical practice.

    Previously, Mirena® was licensed as an IUS providing effective contraception for 6 years and for the treatment of idiopathic menorrhagia for 5 years. However, Mirena® can now remain in place for an additional 3 years if symptoms of HMB have not returned earlier and in those who wish to continue contraception with this method1

     

    All in all, Mirena® can now remain in place to provide contraception in maximum for up to 8 years.

    Mirena® remains highly effective, providing your patients the peace of mind of continuous contraception for an additional 3 years. In an open-label extension study (N=362) there was a 0.68% cumulative pregnancy rate in Years 6–8 of Mirena® use. This was independent of patient compliance, while age and parity showed no important differences.1

     

    • Jensen JT et al. Am J Obstet Gynecol 2022;227(6):873.e1–873.e12. Return to content

    Mirena® is a long-acting reversible contraceptive method that can be particularly useful in women with heavy menstrual bleeding.1

    Mirena® maintains a favorable benefit/risk profile through 8 years of use.1 For full benefit/risk information, please see the Mirena® SmPC.2

    If your patient wishes to continue contraception, Mirena® can now remain in place for up to 8 years.

     

    At the end of 8 years, it must be removed and replaced with a new Mirena® if the patient chooses to continue contraception with this IUS.1

    As long as symptoms of HMB remain controlled, Mirena® can stay in place for up to 8 years. In case symptoms of HMB return, Mirena® should be removed and replaced, if medically appropriate. For all women using Mirena®, the IUS must be removed after 8 years of use.1